Regenerative medicine is the process of replacing, or regenerating, human cells, tissues or organs to restore or establish normal function.
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Degeneration or pain in your ankle or foot can be quite dangerous. That is because we use our ankles and feet all day, every day. When an individual puts weight on an ankle or foot that is injured, it cannot only cause pain, but their gait can be thrown off. Further, a changed gait can stimulate more problems with posture or the joint surrounding it. HCTP can help with ankle and foot pain, plantar fasciitis, arthritis and stiffness, swelling and inflammation.
Elbow pain is a common condition, especially from overuse. Your forearm is connected to your upper arm by the elbow. That means the elbow has connective tissues that surround it (and plenty of them, at that). Keeping that in mind, many things are capable of going wrong with these connections. You could experience a pinched nerve, tendon tear, or overuse syndrome. When such injuries come about, they result in elbow pain that can affect your activities and become debilitating. HCTP can help with chronic elbow pain, tennis elbow (lateral epicondylitis), golfer’s elbow (medial epicondylitis), stiffness, swelling and inflammation.
The hip joint is intended to offer weight bearing activity and stability. It helps us with bending, squatting, and staying active. The areas where hip pain is experienced can be simply annoying or debilitating. Further, hip conditions might throw off not only your gait, but your posture as well. If your hip pain is left unattended, other conditions may come about throughout the rest of your spine. HCTP can help with hip pain, hip bursitis, labrum tear, hip osteoarthritis, stiffness, swelling and inflammation.
The knee joint is the largest and most complex joint in the body. It joins together the thigh bone, shin bone, fibula and kneecap. Because of its complex structure, the knee is often the most stressed joint in the body. The knee joint is intended for weight bearing as well as movement. The areas where knee pain is experienced can be simply annoying or debilitating. HCTP can help with knee pain, meniscus tears, PLC/ACL injuries, runner’s knee (chondromalacia), knee degeneration, arthritis, stiffness, swelling and inflammation.
Neck and back pain are some of the most common conditions that people face. The spine allows us to walk, move, and stay upright. People who experience extreme back pain might be fairly limited, as far as physical activity is concerned. If pain becomes so severe that it prevents you from walking, it can affect the types of activities you can do and lead to a lower quality of life. HCTP can help with chronic neck and back pain, degenerative disc disease, disc bulges and herniations, arthritis, stiffness, swelling and inflammation.
Wrists and hands are utilized for just about everything we do. As such, pain experienced in such areas can limit the things we do significantly. lf we can’t properly use our hands and wrists, then we won’t be able to perform daily tasks that we are accustomed to, whether that involves picking something up, eating food, or typing on a keyboard. HCTP can help with chronic wrist and hand pain, carpal tunnel syndrome, trigger finger, wrist arthritis, stiffness, swelling and inflammation.
Also derived from birth tissue within the umbilical cord is the Wharton’s Jelly. Wharton’s Jelly is the tissue surrounding the umbilical vein and vessels in the cord. When the vessels are removed closer to the fetal side of the cord, you have remaining tissue which contains cells termed medicinal signaling cells or MSCs. MSCs are undifferentiated cells (not changed) that can change into any specific cell type in the body. These cells, once deployed to any area of injury or disease, can readily change into the cell type that is needed to repair. Moreover, MSCs are directed to the body’s cell signals that recruit them to the site of the injury. Once they reach this area, they dock and begin repairing by releasing cytokines, growth factors and other components that are needed in the healing process. When the vessels are removed closer to the maternal side of the umbilical cord, this tissue contains up to 50 times more growth factors and other components than the amniotic fluid, but does not contain MSCs. Wharton’s Jelly products are especially beneficial for patients over forty that, due to the aging process, have less viable cells than a younger patient would have.
Umbilical cord blood is blood that remains in the placenta and the attached umbilical cord after childbirth. Umbilical cord blood contains two types of cells, primarily hematopoietic stem cells (immature cells that can develop into all types of blood cells, including white blood cells, red blood cells, and platelets) and a small number of medicinal signaling cells (plays an important role in many regeneration processes in the human body). These cells have the capacity to self-renewal, release growth factors and cytokines, as well as change into more mature cells. As an extension of fetal cells, umbilical cord blood cells exhibit high plasticity. Umbilical cord cells have been used for over twenty years for hematopoietic cell reconstitution as a substitution for bone marrow reconstitution. Additionally, due to the high plasticity of umbilical cord cells, there is a significantly decreased risk of graft-versus-host disease (GVHD) and if GVHD does occur it is less severe than most other types of transplants.
Older cells are less robust in the production of components necessary for healing. One option for older patients seeking regenerative medicine treatments is exosomes. Exosomes provide many therapeutic benefits by exhibiting regenerative and immune responses that assist the cells contained within the body to heal and correct. Not all cells in the body are active. Some lie dormant, not working to complete the needs of the body. This population of cells are particularly versatile and once activated, penetrate or travel to the sites of injury where they can develop specific characteristics to repair and remodel. Exosomes possess the capability to activate these dormant cells. Exosomes derived from healthy connective tissue cells do not contain DNA.
This means that there is no risk of cells developing cancerous characteristics. Additionally, as the cells contained within do not come from the patient’s own body, the number of cells is not limited by the patient’s age.
Often misrepresented as stem cell therapy, PRP is created by drawing blood from a patient with an anticoagulant, injecting it in a special tube and placing the tube in a centrifuge. The high speed of the centrifuge separates the platelets from the red blood cells. The product is then re-coagulated and sometimes mixed with calcium chloride (calcium salt and an inorganic chloride) to induce the release of growth factors. The PRP is then ready to be used as an autologous tissue (cells or tissues obtained from the same individual) injection or introduced to a surgical site.
Platelets are normally known for their responsibility to clot blood, but they also contain proteins known as growth factors that play a vital role in healing injuries. Since the location of most sports injuries does not receive an abundant flow of blood, the injuries are deprived of the platelets and growth factors needed to regenerate damaged tissue.
Studies show that PRP treatment can resolve that problem by delivering the injured part of the body with the platelets necessary to support healing. While not as “potent” as other therapies, PRP does contain growth factors and other cytokines that are said to recruit cells to an area of injury to coordinate a repair response. Additionally, PRP activates tenocytes to proliferate quickly and produce collagen to repair tissue. PRP is said to begin working in a few weeks but, alone, can take 6-9 months for its full effect. However, PRP mixed with certain products may enhance the healing process and cut the time down by more than eighty percent.
Pain for most of us comes and goes; some stays and you live with it day in and day out. Imagine a life where pain is constant, taking control of you and, in some ways, the life of those close to you. Imagine having to rely on a narcotic to somewhat lessen the pain just to make it through the day. Drugs are typically the first line of treatment for most forms of pain. To date, the goal of successful pain management is to effectively control patient pain without causing side effects from the medication prescribed. Common prescription medications that can be considered for management of acute and chronic pain are often opioids. Although effective for moderate to severe acute pain, the effectiveness of opioids beyond three months requires more evidence. With the effectiveness of opioid medications for pain management in question, many find the risks outweigh the benefits. Side-effects from opioid use can be severe, including addiction and potential overdose. People suffering from chronic pain are in constant search for alternative treatments with fewer side effects and long-lasting relief.
As recent studies increasingly prove the inefficiency and harm of commonly-used treatments like anti-inflammatory medications and corticosteroid injections, more people are seeking regenerative medicine therapies to heal. Regenerative medicine is now at the forefront of offering treatments to help people of all ages overcome pain and injuries in the hip, knee, elbow, ankle, shoulder and foot. Since tendons, ligaments, cartilage, and bones in these areas of the body don’t receive a great deal of blood flow, the body can’t always heal and regenerate itself effectively. Regenerative medicine offers new and efficient treatment options that can augment the body’s natural healing process and rebuild damaged tissue, with the potential to avoid surgery or invasive measures in the future.
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